Allogeneic bone marrow transplantation possibly induces a localized type of porokeratosis

A 15-year-old girl underwent allogenic bone marrow transplantation for neuroblastoma. few years later, she noticed a round lesion on her left buttock. Since the had been asymptomatic and never grown, more than 20 passed before saw local doctor to consult about it. Although was suspected be tinea corporis, no fungi were found microscopic examination. Subsequently, administered topical corticosteroids not effective. She referred our hospital further evaluation, skin biopsy confirmed diagnosis of porokeratosis. There possibility that chemotherapy, total body radiation, or immunosuppressive therapy associated with allogeneic involved in development Numerous cases acquired porokeratosis immunocompromised status have observed; as those after transplantation, 12 reported English literature, 4 which only one lesions limited area surface. Our case relatively uncommon solitary comparatively large. In localized type porokeratosis, it suggested malignant tumor developed earlier other types. Careful follow-up transformation is especially required.